Diagnosis and management of Henoch-Schönlein purpura in pregnancy: a review of the literature

Abstract

Introduction: Henoch-Schönlein Purpura (HSP) is an IgA-mediated hypersensitivity vasculitis uncommon in adults and rarely described in pregnancy. So far, only 20 cases have been described in pregnancy in the worldwide literature. Although prognosis for this condition is reported as excellent, most studies are based on the paediatric population. Henoch-Schönlein Purpura is known to be more severe in adults, and women with a history of HSP have an increased risk of complications during pregnancy. Diagnosis and management of HSP in adults is based on limited evidence, with little data regarding the obstetric population.

Material and methods: Review of data cited in current published cases.

Conclusion: We review the obstetric cases reported so far and discuss diagnostic matters and current management strategies.