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. 2012 Jul;53(7):483-6.
doi: 10.4111/kju.2012.53.7.483. Epub 2012 Jul 19.

Clinical efficacy in the treatment of overactive bladder refractory to anticholinergics by posterior tibial nerve stimulation

Miguel Angel Arrabal-Polo  1 , Francisco Palao-Yago, Iluminada Campon-Pacheco, Maribel Martinez-Sanchez, Armando Zuluaga-Gomez, Miguel Arrabal-Martin
Affiliations

Clinical efficacy in the treatment of overactive bladder refractory to anticholinergics by posterior tibial nerve stimulation

Miguel Angel Arrabal-Polo et al. Korean J Urol. 2012 Jul.

Abstract

Purpose: Overactive bladder (OAB) is a clinical syndrome that is currently treated initially with anticholinergics, although some other therapeutic alternatives exist, such as neuromodulation, botulinum toxin, and posterior tibial nerve stimulation (PTNS). The purpose of this study was to assess the efficacy of PTNS in patients with OAB refractory to anticholinergics.

Materials and methods: We present a cohort study of 14 women with OAB to whom we applied PTNS. We assessed (before and after the treatment) the diurnal micturitional frequency, the nocturnal micturitional frequency, urgency episodes, and urge incontinence episodes. Results were analyzed by using the Wilcoxon test for nonparametric samples.

Results: We observed statistically significant improvement in the diurnal micturitional frequency (p=0.05), in episodes of micturitional urgency (p=0.03), and in episodes of urge incontinence (p=0.004). A total of 50% of the patients felt subjective improvement from their pathology.

Conclusions: PTNS is a valid, minimally invasive treatment option with minimum morbidity for patients with OAB refractory to treatment with anticholinergics.

Keywords: Cholinergics antagonist; Tibial nerve; Urinary bladder overactive.

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Conflict of interest statement

The authors have nothing to disclose.

Figures

FIG. 1
FIG. 1
Changes in the principal parameters studied.
See this image and copyright information in PMC

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