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Case Reports
. 2012 Jul;28(3):368-70.
doi: 10.4103/0970-9185.98346.

Midazolam-induced acute dystonia reversed by diazepam

Mustafa Komur  1 , Ali Ertug Arslankoylu, Cetin Okuyaz
Affiliations
Case Reports

Midazolam-induced acute dystonia reversed by diazepam

Mustafa Komur et al. J Anaesthesiol Clin Pharmacol. 2012 Jul.

Abstract

Midazolam can induce acute dystonia in childhood. We report the development of acute dystonia in a 6-year-old girl after receiving midazolam as a sedative. Dystonic contractions persisted despite flumazenil and biperiden lactate injections and the patient was treated with diazepam. Acute dystonia was rapidly abolished after the administration of diazepam intravenously. Diazepam may be an effective treatment option in patients who are unresponsive to flumazenil.

Keywords: Acute dystonia; diazepam; midazolam.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Normal T2 weighted and FLAIR magnetic resonance images of basal ganglias
See this image and copyright information in PMC

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