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. 2012 Aug;26(4):260-4.
doi: 10.3341/kjo.2012.26.4.260. Epub 2012 Jul 24.

Systemic factors associated with central serous chorioretinopathy in Koreans

Youngsub Eom  1 , Jaeryung Oh, Seong-Woo Kim, Kuhl Huh
Affiliations

Systemic factors associated with central serous chorioretinopathy in Koreans

Youngsub Eom et al. Korean J Ophthalmol. 2012 Aug.

Abstract

Purpose: To investigate systemic factors associated with central serous chorioretinopathy (CSC).

Methods: We retrospectively reviewed the medical records of 113 Korean patients who were diagnosed with CSC and who underwent history taking with a specialized questionnaire for CSC. They were matched for age and gender at a ratio of 1 : 3 to 339 normal controls. Normal controls were consecutively selected from a database at the Health Promotion Center. General characteristics and medical histories were compared between the two groups. The statistical analyses used included independent t-test, Mann-Whitney test, Fisher's exact test, and multivariate logistic regression analysis.

Results: There were 90 men and 23 women in the CSC group, and the male-female ratio for both groups was 3.9 : 1. The mean age of the patients was 45.6 years. In multivariate analysis, hypertension (odds ratio [OR], 2.327; 95% confidence interval [CI], 1.349-4.013), use of medicinal plants (OR, 2.198; 95% CI, 1.193-4.049), sleep disturbances (OR, 1.732; 95% CI, 1.096-2.739), and snoring (OR, 1.727; 95% CI, 1.058-2.820) were strongly associated with CSC.

Conclusions: Hypertension, sleep disturbance, snoring, and medicinal plant use were identified as factors associated with CSC. Expanded history taking, including systemic factors and culture-specific behavior related to stress or fatigue such as use of medicinal plants, will be helpful in identifying Korean patients at an increased risk for CSC.

Keywords: Central serous chorioretinopathy; Fatigue, Medicinal plants; Sleep; Snoring.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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