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. 2011 Jan;2(1):49-53.
doi: 10.3892/ol.2010.223. Epub 2010 Nov 23.

Medullary thyroid carcinoma: The third most common thyroid cancer reviewed

Michael Stamatakos  1 , Panoraia Paraskeva, Charikleia Stefanaki, Paraskevas Katsaronis, Andreas Lazaris, Konstantinos Safioleas, Konstantinos Kontzoglou
Affiliations

Medullary thyroid carcinoma: The third most common thyroid cancer reviewed

Michael Stamatakos et al. Oncol Lett. 2011 Jan.

Abstract

Medullary thyroid cancer is a type of thyroid cancer of neuroendocrine origin. It occurs in hereditary and sporadic forms, and its aggressive behavior is associated with the clinical presentation and type of RET mutation. Total thyroidectomy remains the ideal choice of treatment. Early diagnosis and treatment are the fundamental for a 100% cure rate. In this study, we present our experience of 3 cases, along with a complete review of the literature derived from a Pubmed Database search.

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Figures

Figure 1
Figure 1
Nests of malignant cells surrounding normal thyroid follicles. Hematoxylin and eosin staining; magnification, ×100.
Figure 2
Figure 2
Morphological features of neoplastic cells. Hematoxylin and eosin staining; magnification, ×400.
Figure 3
Figure 3
Congo red staining was not diagnostic for amyloid deposits. Magnification, ×100.
See this image and copyright information in PMC

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