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Case Reports
. 2012 Oct;206(8):1275-9.
doi: 10.1093/infdis/jis490. Epub 2012 Aug 7.

Symptomatic infection and detection of vaccine and vaccine-reassortant rotavirus strains in 5 children: a case series

Julie A Boom  1 , Leila C Sahni, Daniel C Payne, Rashi Gautam, Freda Lyde, Slavica Mijatovic-Rustempasic, Michael D Bowen, Jacqueline E Tate, Marcia A Rench, Jon R Gentsch, Umesh D Parashar, Carol J Baker
Affiliations
Case Reports

Symptomatic infection and detection of vaccine and vaccine-reassortant rotavirus strains in 5 children: a case series

Julie A Boom et al. J Infect Dis. 2012 Oct.

Abstract

Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009-2010. Four strains were related to pentavalent rotavirus vaccine, whereas one was related to monovalent rotavirus vaccine. The contribution of these strains to each patient's illness was unclear given that 2 patients had prominent respiratory symptoms and 2 were concurrently infected with another pathogen (group F adenovirus and norovirus). Continued monitoring is necessary to assess the role of vaccine strains and vaccine-reassortant strains in pediatric rotavirus infections.

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