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Review
. 2012 Nov 1;53(6):815-22.
doi: 10.1093/jrr/rrs036. Epub 2012 Aug 7.

Does ionizing radiation influence Alzheimer's disease risk?

Nasrin Begum  1 , Bing Wang, Masahiko Mori, Guillaume Vares
Affiliations
Review

Does ionizing radiation influence Alzheimer's disease risk?

Nasrin Begum et al. J Radiat Res. .

Abstract

Alzheimer's disease (AD) is a human neurodegenerative disease, and its global prevalence is predicted to increase dramatically in the following decades. There is mounting evidence describing the effects of ionizing radiation (IR) on the brain, suggesting that exposure to IR might ultimately favor the development of AD. Therefore better understanding the possible connections between exposure to IR and AD pathogenesis is of utmost importance. In this review, recent developments in the research on the biological and cognitive effects of IR in the brain will be explored. Because AD is largely an age-related pathology, the effects of IR on ageing will be investigated.

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