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. 2012 Jun;7(3):197-202.
doi: 10.1159/000339671. Epub 2012 Jun 27.

Fertility Preservation Methods in Breast Cancer

Fedro A Peccatori  1 , Lino Del Pup, Francesca Salvagno, Maurizio Guido, Maria A Sarno, Alberto Revelli, Luisa Delle Piane, Elisabetta Dolfin, Dorella Franchi, Emanuela Molinari, Valentina Immediata, Leonora Chiavari, Alessandra Vucetich, Andrea Borini
Affiliations

Fertility Preservation Methods in Breast Cancer

Fedro A Peccatori et al. Breast Care (Basel). 2012 Jun.

Abstract
in English, German

Thanks to the recent advances in reproductive medicine, more and more young women with breast cancer may be offered the possibility of preserving their fertility. Fertility can be endangered by chemotherapy, by treatment duration and by patient's age at diagnosis. The currently available means to preserve a young woman's fertility are pharmacological protection with gonadotrophin-releasing hormone analogues during chemotherapy, and ovarian tissue or oocyte/embryo freezing before treatment. New future venues, including in vitro maturation, will improve the feasibility and efficacy of the fertility preservation methods in breast cancer patients.

Dank der Fortschritte in der Reproduktionsmedizin kann jungen Frauen mit Brustkrebs ein Fertilitätserhalt angeboten werden. Die Fruchtbarkeit kann durch Chemotherapie, die Dauer der Behandlung und durch das Alter der Patientin bei Diagnose gefährdet sein. Die derzeit verfügbaren Methoden, die Fruchtbarkeit einer jungen Frau zu erhalten, umfassen den pharmakologischen Schutz mit Gonadotropin-releasing-hormone-Analoga während der Chemotherapie und Cryopreservation von Ovarialgewebe, Oozyten oder Embryonen vor der Therapie. Zukünftige neue Möglichkeiten, z.B. In-vitro-Reifung, werden die Durchführbarkeit und Effektivität des Fertilitäts-erhalts weiter verbessern.

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