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. 2012 Aug;27(8):969-71.
doi: 10.3346/jkms.2012.27.8.969. Epub 2012 Jul 25.

Clinical factors associated with hepatitis A virus seropositivity in HIV-infected adults living in a country with an epidemiologic shift for hepatitis A virus infection

Ji Hyeon Baek  1 , Chang Oh Kim, Jun Yong Park, Su Jin Jeong, Nam Soo Koo, Hye Won Kim, Sang Hoon Han, Jun Yong Choi, Young Goo Song, June Myung Kim
Affiliations

Clinical factors associated with hepatitis A virus seropositivity in HIV-infected adults living in a country with an epidemiologic shift for hepatitis A virus infection

Ji Hyeon Baek et al. J Korean Med Sci. 2012 Aug.

Abstract

The number of HIV-infected individuals susceptible to Hepatitis A virus (HAV) infection is increasing in Korea; however, it has proven difficult to devise a vaccination policy therefore because limited seroepidemiologic data exists for them. Accordingly, anti-HAV IgG was measured in 188 HIV-infected adults between July 2008 and July 2010. The nadir CD4+ T lymphocyte counts were not different between the HAV-positive and -negative groups (197 ± 138 vs 202 ± 129, P = 0.821). The only factor independently associated with seropositive status was age under 40 yr old (OR 0.017, P < 0.001). Our findings suggest that HAV vaccination in HIV-infected adults should be targeted at persons under the age of 40 yr.

Keywords: HAV; HIV; Seropositivity.

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