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Comment
. 2012 Aug 9;120(6):1151-2.
doi: 10.1182/blood-2012-06-433177.

Autologous T cells on the attack against AML

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Autologous T cells on the attack against AML

Zwi N Berneman. Blood. .
Free article

Abstract

In this issue of Blood, Greiner and colleagues describe how peptides derived from the mutated nucleophosmin 1 gene (NPM1(mut)) can elicit in vitro CD4(+) and CD8(+) T-cell responses in patients with acute myeloid leukemia, which can lead to antigen-specific lysis of leukemic blasts.

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