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Controlled Clinical Trial
. 2012 May 22;92(19):1334-6.

[Efficacy and safety of insulin aspart versus regular human insulin for women with gestational diabetes mellitus]

[Article in Chinese]
Li Zhou  1 , Ling Fan
Affiliations
  • PMID: 22883122
Controlled Clinical Trial

[Efficacy and safety of insulin aspart versus regular human insulin for women with gestational diabetes mellitus]

[Article in Chinese]
Li Zhou et al. Zhonghua Yi Xue Za Zhi. .

Abstract

Objective: To explore the efficacy and safety of human aspart versus regular human insulin in women with gestational diabetes mellitus (GDM).

Methods: A total of 80 women with GDM during pregnancy delivered at our hospital divided into 2 groups: Group 1 with human aspart and regular human insulin N while Group 2 with regular human insulin R and N. The levels of glucose were compared before and after 2 h at breakfast, lunch and supper at Day 1, 3 and 5. And the outcomes of women and their babies were evaluated.

Results: No significant difference in general characteristics existed between two groups. Except for breakfast of Day 3, no significant difference was found in terms of the amount of insulin, the time of satisfactory glucose level and delivery time point, etc. There was no significant inter-group difference in the outcomes of pregnant women and their babies.

Conclusion: The efficacy and safety of human aspart or regular human insulin are comparable for the women with gestational diabetes mellitus.

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