[Epidemiological survey on lipid levels in adults with Han, Uygur and Kazakh ethnicities from Xinjiang, China]

Abstract

Objective: To investigate the prevalence rates of triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol in Han, Uygur and Kazakh populations aged over 35 years, in Xinjiang area.

Methods: A four-stage randomly selected samples were used to analyze the prevalence rates of lipid levels in different nationalities, ages, sexes based on data from 7 areas in Xinjiang.

Results: (1) TG levels in Xinjiang appeared to be the highest in Han and lowest in Kazakh ethnicities with the means as (1.72 ± 1.45) mmol/L, (1.21 ± 0.93) mmol/L (F = 209.272, P = 0.000) respectively. The highest TC levels were seen in Kazakh with the lowest seen in Uygur, with means as (4.78 ± 1.16) mmol/L, (4.37 ± 1.13) mmol/L (F = 168.796, P = 0.000) respectively. Both HDL-C and LDL-C levels in Kazakh were the highest but remained the same level in Han and Uygur. (2) The value of TG reached the peak at age 45 to 54 in Han and Uygur, and then descending along with ageing. The overall TC level increased along with age but the HDL-C level generally declined with ageing. The LDL-C level showed a waving distribution along with the increase of age. (3) The TG levels were seen higher in men than in women among Han, Uygur and Kazakh but the TC levels of Han and Uygur were lower in men than in women. Both HDL-C and LDL-C levels were also lower in Han and Kazakh males than in females. (4) The prevalence rates of abnormalities were 35.12%, 32.57% and 16.44% on TG; 27.83%, 17.05% and 33.43% on TC; 32.68%, 31.73% and 28.72% HDL-C; 36.95%, 37.02% and 38.00% on LDL-C, respectively.

Conclusion: People with Han and Uygur ethnicities in Xinjiang region had high TG, but low HDL-C distribution of blood lipids while the Kazakh had low TG, high TC, high HDL-C, high LDL-C blood lipids distribution. The distributions of TG levels were different in age, nationality and sex, except the distribution of LDL-C levels. More attention should be paid to the young men of Han and Uygur on prevention of dyslipidemia, in Xinjiang.