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Comment
. 2012 Aug 9;75(3):356-7.
doi: 10.1016/j.neuron.2012.07.017.

mTOR signaling fades POMC neurons during aging

Jae Geun Kim  1 , Tamas L Horvath
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mTOR signaling fades POMC neurons during aging

Jae Geun Kim et al. Neuron. .
Free article

Abstract

Hypothalamic POMC neurons contribute to the regulation of energy homeostasis and glucose metabolism. In this issue of Neuron, Yang et al. (2012) show that the mTOR pathway has a pivotal role in deterioration of POMC neurons during age-dependent obesity.

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