doi: 10.1002/anie.201204505.
Epub 2012 Aug 9.
α-Selective organocatalytic synthesis of 2-deoxygalactosides
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- PMID: 22887611
- DOI: 10.1002/anie.201204505
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α-Selective organocatalytic synthesis of 2-deoxygalactosides
Angew Chem Int Ed Engl.
.
Abstract
Alpha rules: A thiourea acts as an efficient organocatalyst for the glycosylation of protected galactals to form oligosaccharides containing a 2-deoxymonosaccharide moiety. The reaction is highly stereoselective for α-linkages and proceeds by way of a syn-addition mechanism.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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