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Review
. 2012 Sep 3;51(36):8960-9009.
doi: 10.1002/anie.201201666. Epub 2012 Aug 6.

C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals

Junichiro Yamaguchi  1 , Atsushi D Yamaguchi, Kenichiro Itami
Affiliations
Review

C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals

Junichiro Yamaguchi et al. Angew Chem Int Ed Engl. .

Abstract

The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.

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