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Comment
. 2012 Aug 14;23(2):234-6.
doi: 10.1016/j.devcel.2012.07.018.

Sensing mitochondrial homeostasis: the protein import machinery takes control

F-Nora Vögtle  1 , Chris Meisinger
Affiliations
Comment

Sensing mitochondrial homeostasis: the protein import machinery takes control

F-Nora Vögtle et al. Dev Cell. .

Erratum in

  • Dev Cell. 2012 Sep 11;23(3):674

Abstract

Mitochondrial homeostasis is maintained by several quality control mechanisms, including an unfolded protein response that in turn elicits a transcriptional response. In a recent issue of Science, Nargund et al. (2012) propose a sensing mechanism for unfolded proteins' accumulation in the mitochondrial matrix that involves the mitochondrial protein import machinery.

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