Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Mar;98(3):e23-4.
doi: 10.3324/haematol.2012.072140. Epub 2012 Aug 16.

Common genetic variation contributes significantly to the risk of developing chronic lymphocytic leukemia

Maria Chiara Di Bernardo, Peter Broderick, Daniel Catovsky, Richard S Houlston

Common genetic variation contributes significantly to the risk of developing chronic lymphocytic leukemia

Maria Chiara Di Bernardo et al. Haematologica. 2013 Mar.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Quantile-Quantile plots of observed test statistics (χ2) for association with CLL. The plot in blue shows test statistics for all SNPs, whereas the plot in green shows test statistics excluding SNPs mapping to previously identified risk loci. The black line represents the null hypothesis of no true association.
See this image and copyright information in PMC

References

    1. Di Bernardo MC, Crowther-Swanepoel D, Broderick P, Webb E, Sellick G, Wild R, et al. A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet. 2008;40(10):1204–10 - PubMed
    1. Crowther-Swanepoel D, Broderick P, Di Bernardo MC, Dobbins SE, Torres M, Mansouri M, et al. Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nat Genet. 2010;42(2):132–6 - PMC - PubMed
    1. Crowther-Swanepoel D, Di Bernardo MC, Jamroziak K, Karabon L, Frydecka I, Deaglio S, et al. Common genetic variation at 15q25.2 impacts on chronic lymphocytic leukaemia risk. Br J Haematol. 2011;154(2):229–33 - PubMed
    1. Lee SH, Wray NR, Goddard ME, Visscher PM. Estimating missing heritability for disease from genome-wide association studies. Am J Hum Genet. 2011;88(3):294–305 - PMC - PubMed
    1. Power C, Elliott J. Cohort profile: 1958 British birth cohort (National Child Development Study). Int J Epidemiol. 2006;35(1):34–41 - PubMed

Publication types