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Review
. 2012 Jul;3(7):889-900.
doi: 10.4155/tde.12.68.

High-dose monoclonal antibodies via the subcutaneous route: challenges and technical solutions, an industry perspective

Chakravarthy Narasimhan  1 , Henryk Mach, Mohammed Shameem
Affiliations
Review

High-dose monoclonal antibodies via the subcutaneous route: challenges and technical solutions, an industry perspective

Chakravarthy Narasimhan et al. Ther Deliv. 2012 Jul.

Abstract

This review summarizes the various challenges in product development involved in subcutaneous administration of high-dose monoclonal antibodies and attempts to provide an industry perspective of some of the available technologies and potential avenues to overcome these challenges.

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