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. 2012 Oct;18(10):819-26.
doi: 10.1111/j.1755-5949.2012.00378.x. Epub 2012 Aug 20.

Age differences in clinical characteristics, health care, and outcomes after ischemic stroke in China

Ya-Xian Deng  1 , Yi-Long Wang, Bao-Qin Gao, Chun-Xue Wang, Xing-Quan Zhao, Li-Ping Liu, An-Xin Wang, Yong Zhou, Gai-Fen Liu, Wan-Liang Du, Ning Zhang, Jing Jing, Xia Meng, Jie Xu, Lin-Yu Wang, Yong-Jun Wang
Affiliations

Age differences in clinical characteristics, health care, and outcomes after ischemic stroke in China

Ya-Xian Deng et al. CNS Neurosci Ther. 2012 Oct.

Abstract

Background and purpose: Little information is available on the effects of age on health care and outcomes of ischemic stroke (IS) in China. Our aim was to evaluated risk factors, health care, and outcomes among age groups including ≤ 45, 46-65, 66-79, and ≥ 80 years and to find whether the outcome was affected by age and health care.

Methods: CNSR is a nationwide prospective registry for patients admitted with acute stroke and prospectively followed up 12-month outcomes. Demographics, socioeconomics, risk factors, health care, and outcomes were analyzed among age groups, and multivariate regression analysis was used to determine the association of outcome and age and health care.

Results: We identified 12,415 acute IS patients for analysis. Of 1179 (9.50%) were aged ≥ 80 years. In terms of risk factors, cardiac diseases were significantly more frequent in patients ≥ 80 years, behavioral risk factors were more common in younger patients, and hypertension, hyperlipidemia, and diabetes were more seen in 46-79 patients. The use of health care varied among groups and was significantly lower in ≥ 80 years especially in secondary prevention. The very old patients had the worst outcomes even after adjusting by prognostic factors; however, adjusting forward by health care, the extent of differences decreased.

Conclusions: In CNSR, differences in stroke clinic characteristics and health care were observed among various age groups, and the old patients, receiving lower levels of stroke care, had the worst outcomes. Knowledge of the age differences in ischemic stroke may be helpful to appropriately allocate the limited health resources and to improve stroke outcomes.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow diagram defining the studying patients with IS. CNSR, indicates China National Stroke Registry; ICH, intracerebral haemorrhage; IS, ischemic stroke; TIA, transient ischemic attack.
Figure 2
Figure 2
Outcomes of 12‐month after onset according to age group.
See this image and copyright information in PMC

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