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. 2012 Aug 17;150(4):671-2.
doi: 10.1016/j.cell.2012.07.026.

Poxvirus use a "gene accordion" to tune out host defenses

John R Roth  1 , D I Andersson
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Poxvirus use a "gene accordion" to tune out host defenses

John R Roth et al. Cell. .
Free article

Abstract

A multistep process of gene amplification, mutation, and reduction allows poxvirus to overcome host antiviral defenses. The mechanism speeds genetic adaptation and promises to be broadly applicable in many biological settings.

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