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Review
. 2012 Nov;188(11):975-81.
doi: 10.1007/s00066-012-0170-8. Epub 2012 Aug 22.

Anti-inflammatory effects of low-dose radiotherapy. Indications, dose, and radiobiological mechanisms involved

M Arenas  1 , S Sabater, V Hernández, A Rovirosa, P C Lara, A Biete, J Panés
Affiliations
Free article
Review

Anti-inflammatory effects of low-dose radiotherapy. Indications, dose, and radiobiological mechanisms involved

M Arenas et al. Strahlenther Onkol. 2012 Nov.
Free article

Abstract

Low-dose radiotherapy (LD-RT) has been used for several benign diseases, including arthrodegenerative and inflammatory pathologies. Despite its effectiveness in clinical practice, little is known about the mechanisms through which LD-RT modulates the various phases of the inflammatory response and about the optimal dose fractionation. The objective of this review is to deepen knowledge about the most effective LD-RT treatment schedule and radiobiological mechanisms underlying the anti-inflammatory effects of LD-RT in various in vitro experiments, in vivo studies, and clinical studies.

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