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Multicenter Study
. 2012 Nov;56(11):6003-5.
doi: 10.1128/AAC.00745-12. Epub 2012 Aug 20.

Changing epidemiology of extended-spectrum β-lactamases in Argentina: emergence of CTX-M-15

S Sennati  1 , G Santella, J Di Conza, L Pallecchi, M Pino, B Ghiglione, G M Rossolini, M Radice, G Gutkind
Affiliations
Multicenter Study

Changing epidemiology of extended-spectrum β-lactamases in Argentina: emergence of CTX-M-15

S Sennati et al. Antimicrob Agents Chemother. 2012 Nov.

Abstract

A multicenter survey, carried out in 2010 in Argentina, showed an increased prevalence of extended-spectrum β-lactamase (ESBL)-producing enterobacteria, with some changes in the molecular epidemiology of circulating ESBLs. While enzymes of the CTX-M-2 group remain endemic, the emergence of CTX-M-15 and of enzymes of the CTX-M-8 and CTX-M-9 groups was observed. The CTX-M-15-positive isolates represented 40% of CTX-M producers and included representatives of Escherichia coli ST131 and Klebsiella pneumoniae ST11.

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