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. 2012 Jun;7(Suppl 1):20-3.
doi: 10.1007/s11789-012-0047-5.

Lipid apheresis techniques: current status in Germany

Peter Grützmacher  1 , Claudius Kleinert
Affiliations

Lipid apheresis techniques: current status in Germany

Peter Grützmacher et al. Clin Res Cardiol Suppl. 2012 Jun.

Abstract

For long-term lipid apheresis therapy, several different technical systems have been developed which enable effective reduction of LDL cholesterol and other atherogenic lipoproteins, such as Lp(a), with sufficient selectivity and good clinical tolerance. Suitable techniques include whole blood adsorption with polyacrylamide and dextran sulfate cellulose, while primary plasma separation is used for cascade filtration, heparin-induced precipitation, immunoadsorption, silicate gel adsorption, and dextran sulfate cellulose (both techniques). The technical features are described. Only intensive training and experience of the medical personnel guarantees reliable treatment safety of all systems at a very low rate of minor side effects.

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