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Review
. 2013 Mar;19(2):111-20.
doi: 10.1111/j.1601-0825.2012.01962.x. Epub 2012 Aug 23.

Genome-wide approaches (GWA) in oral and craniofacial diseases research

H Kim  1 , S Gordon, R Dionne
Affiliations
Review

Genome-wide approaches (GWA) in oral and craniofacial diseases research

H Kim et al. Oral Dis. 2013 Mar.

Abstract

Oral Diseases (2012) Underlying molecular genetic mechanisms of diseases can be deciphered with unbiased strategies using recently developed technologies enabling genome-wide scale investigations. These technologies have been applied in scanning for genetic variations, gene expression profiles, and epigenetic changes for oral and craniofacial diseases. However, these approaches as applied to oral and craniofacial conditions are in the initial stages, and challenges remain to be overcome, including analysis of high throughput data and their interpretation. Here, we review methodology and studies using genome-wide approaches in oral and craniofacial diseases and suggest future directions.

Keywords: craniofacial; genome‐wide; genomics; microarray.

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Figures

Figure 1
Figure 1
Contributions of molecular genetic approaches to the study of oral and craniofacial diseases
See this image and copyright information in PMC

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