Pupillary function in multiple sclerosis
- PMID: 2291401
- DOI: 10.1111/j.1600-0404.1990.tb03323.x
Pupillary function in multiple sclerosis
Abstract
Eighteen MS patients with visual acuity of 20/30 or better and without recent visual complaints, and 14 age- and sex-matched controls were studied by TV pupillography. The response amplitude and the maximum rate of pupillary constriction or dilation of the light, dark, accommodation and ciliospinal reflexes were unchanged. The latency of the pupillary light response (PLR), however, was prolonged and closely related to walking performance (R = 0.76; p less than 0.001). No relationship was established between PLR latency and previous history of optic neuritis or latency of the VEP. It is concluded that MS patients with preserved visual acuity have only discrete autonomic pupillary disturbances and that the PLR delay is related to disease progression.
Similar articles
-
Autonomic involvement in multiple sclerosis: a pupillometric study.Clin Auton Res. 1997 Dec;7(6):315-9. doi: 10.1007/BF02267724. Clin Auton Res. 1997. PMID: 9430804
-
Pupillary light reflex latency in patients with multiple sclerosis.Electroencephalogr Clin Neurophysiol. 1992 Mar;82(3):213-9. doi: 10.1016/0013-4694(92)90170-m. Electroencephalogr Clin Neurophysiol. 1992. PMID: 1371442
-
Analysis of retinal nerve fibre layer, visual evoked potentials and relative afferent pupillary defect in multiple sclerosis patients.Clin Neurophysiol. 2016 Jan;127(1):821-826. doi: 10.1016/j.clinph.2015.06.025. Epub 2015 Jul 4. Clin Neurophysiol. 2016. PMID: 26251105
-
Neuro-ophthalmology.Curr Opin Neurol Neurosurg. 1992 Oct;5(5):740-3. Curr Opin Neurol Neurosurg. 1992. PMID: 1392147 Review.
-
Physiology, assessment, and disorders of the pupil.Curr Opin Ophthalmol. 1999 Dec;10(6):394-400. doi: 10.1097/00055735-199912000-00005. Curr Opin Ophthalmol. 1999. PMID: 10662243 Review.
Cited by
-
Pupillary function in early multiple sclerosis.Clin Auton Res. 2008 Jun;18(3):150-4. doi: 10.1007/s10286-008-0471-2. Epub 2008 May 6. Clin Auton Res. 2008. PMID: 18461280
-
Autonomic involvement in multiple sclerosis: a pupillometric study.Clin Auton Res. 1997 Dec;7(6):315-9. doi: 10.1007/BF02267724. Clin Auton Res. 1997. PMID: 9430804
-
Neurodegenerative Interplay of Cardiovascular Autonomic Dysregulation and the Retina in Early Multiple Sclerosis.Front Neurol. 2019 May 15;10:507. doi: 10.3389/fneur.2019.00507. eCollection 2019. Front Neurol. 2019. PMID: 31156539 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical