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. 2012 Sep;25(9):420-8.
doi: 10.1097/01.ASW.0000419408.37323.0c.

Sickle cell disease and leg ulcers

Barry Ladizinski  1 , Andrea Bazakas, Nisha Mistry, Afsaneh Alavi, R Gary Sibbald, Richard Salcido
Affiliations

Sickle cell disease and leg ulcers

Barry Ladizinski et al. Adv Skin Wound Care. 2012 Sep.

Abstract

Sickle cell disease is a genetic disorder of hemoglobin synthesis leading to a deformation of the red blood cell. This disorder is associated with painful, slow-to-heal leg ulcers. This article discusses the wound bed preparation paradigm as a guide to the treatment of sickle cell-associated leg ulcers.

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