A reliable and reproducible experimental challenge model for peste des petits ruminants virus
- PMID: 22915602
- PMCID: PMC3486268
- DOI: 10.1128/JCM.01785-12
A reliable and reproducible experimental challenge model for peste des petits ruminants virus
Abstract
Experimental challenge protocols that consistently reproduce clinical signs of peste des petits ruminants in Alpine goats infected with a tissue culture-passaged peste des petits ruminants virus are described. The protocols can be used to carry out quality-controlled vaccine efficacy and pathogenesis studies under experimental conditions.
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