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. 1990 Dec;61(6):354-7.
doi: 10.1007/BF01738549.

Function of granulocytes in B-chronic lymphatic leukaemia

D Dekaris  1 , S Handl, A Sabioncello, S Rabatić
Affiliations

Function of granulocytes in B-chronic lymphatic leukaemia

D Dekaris et al. Blut. 1990 Dec.

Abstract

To study the function of granulocytes in patients with B-cell chronic lymphatic leukaemia (B-CLL), granulocytes were separated from peripheral blood of 48 patients (mean age: 69 years) and 35 apparently healthy age-matched volunteers. Spontaneous mobility, ingestion, digestion and antibody dependent cellular cytotoxicity (ADCC) of granulocytes were assessed. Decreased spontaneous mobility was found in granulocytes from patients with B-CLL but between the two groups no detectable differences were encountered in the other parameters tested. No alterations of granulocytes functions were found to be correlated with clinical stages of B-CLL. If granulocytes functions were compared in treated (chlorambucil, steroids) and untreated patients, a significant decrease in digestion was found in treated patients.

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References

    1. Mech Ageing Dev. 1988 Nov 30;45(3):223-9 - PubMed
    1. Clin Exp Immunol. 1985 Aug;61(2):425-32 - PubMed
    1. Cancer Res. 1964 Dec;24:1958-68 - PubMed
    1. J Leukoc Biol. 1986 Apr;39(4):399-407 - PubMed
    1. Biomed Pharmacother. 1986;40(8):308-11 - PubMed