Comment
doi: 10.1016/j.immuni.2012.08.005.
Guanylate-binding proteins: niche recruiters for antimicrobial effectors
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- PMID: 22921115
- DOI: 10.1016/j.immuni.2012.08.005
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Comment
Guanylate-binding proteins: niche recruiters for antimicrobial effectors
Immunity.
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Abstract
There are fundamental questions regarding how IFN-γ activates host cells to eliminate intracellular pathogens. In this issue of Immunity, Yamamoto et al. (2012) demonstrate a critical role for the p65 guanylate-binding proteins (GBPs) in this process during infection with Toxoplasma gondii.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.Immunity. 2012 Aug 24;37(2):302-13. doi: 10.1016/j.immuni.2012.06.009. Epub 2012 Jul 12. Immunity. 2012. PMID: 22795875
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