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Comment
. 2012 Aug 24;37(2):191-3.
doi: 10.1016/j.immuni.2012.08.005.

Guanylate-binding proteins: niche recruiters for antimicrobial effectors

Christopher D Dupont  1 , Christopher A Hunter
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Free article
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Guanylate-binding proteins: niche recruiters for antimicrobial effectors

Christopher D Dupont et al. Immunity. .
Free article

Abstract

There are fundamental questions regarding how IFN-γ activates host cells to eliminate intracellular pathogens. In this issue of Immunity, Yamamoto et al. (2012) demonstrate a critical role for the p65 guanylate-binding proteins (GBPs) in this process during infection with Toxoplasma gondii.

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