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Case Reports
. 2012 Jul;7(3):168-9.
doi: 10.4103/1817-1737.98853.

Pulmonary tumor thrombotic microangiopathy caused by gastric cancer

Hiroko Kuwabara  1 , Shuhei Yoshida, Tasaburo Takasu, Masako Yuki, Isao Goto, Toshiaki Hanafusa, Yuro Shibayama
Affiliations
Case Reports

Pulmonary tumor thrombotic microangiopathy caused by gastric cancer

Hiroko Kuwabara et al. Ann Thorac Med. 2012 Jul.

Abstract

Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal cancer-related pulmonary complication with rapidly progressing dyspnea, and occasionally induces sudden death. Here, we describe a postmortem-diagnosed PTTM case caused by gastric cancer, with the complaint of progressing dyspnea for 5 days.He did not have any abdominal symptoms or cancer history. PTTM should be considered in patients with rapidly worsening respiratory conditions, even if there is no cancer history.

Keywords: Dyspnea; PTTM; gastric cancer.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Chest computed tomography scan showing diffuse tiny nodules and the swelling of bronchovascular bundles
Figure 2
Figure 2
(a) Obstruction of a pulmonary artery (H and E, ×40), (b) High-power view of an artery (H and E, ×400), (c) Immunopositivity for vascular endothelial growth factor among the tumor cells (×200)
See this image and copyright information in PMC

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