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Randomized Controlled Trial
. 2013 Jan;32(1):91-3.
doi: 10.1097/INF.0b013e31826fb32d.

Therapeutic zinc and copper supplementation in acute diarrhea does not influence short-term morbidity and growth: double-blind randomized controlled trial

Archana B Patel  1 , Michael J Dibley, Manju Mamtani, Neetu Badhoniya, Hemant Kulkarni
Affiliations
Randomized Controlled Trial

Therapeutic zinc and copper supplementation in acute diarrhea does not influence short-term morbidity and growth: double-blind randomized controlled trial

Archana B Patel et al. Pediatr Infect Dis J. 2013 Jan.

Abstract

Our objective was to evaluate the effect of zinc and copper supplementation in acute diarrhea on morbidity and growth during 12 weeks of follow-up. In a double-blind randomized controlled clinical trial of 724 children aged 6-59 months, none of the 11 evaluated outcomes showed significant association with zinc or zinc and copper supplementation. Thus, therapeutic zinc supplementation may not always yield short-term -benefits.

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