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Randomized Controlled Trial
. 2012 Sep;13(3):139-49.
doi: 10.1016/j.pmn.2010.07.008. Epub 2011 Jan 5.

Effectiveness of oral sucrose for pain management in infants during immunizations

Donna Miles Curry  1 , Cindy Brown, Sharon Wrona
Affiliations
Randomized Controlled Trial

Effectiveness of oral sucrose for pain management in infants during immunizations

Donna Miles Curry et al. Pain Manag Nurs. 2012 Sep.

Abstract

This study examined the effects of oral sucrose as an analgesic agent during routine immunization for infants at 2, 4, and 6 months of age. A sample of 113 healthy infants were recruited from three ambulatory clinics and randomly assigned to one of three treatment groups. Infants were given 2 mL orally of either 50% sucrose, 75% sucrose, or sterile water 2 minutes before administration of immunizations. No significant difference was found among the different age groups with the different treatments for pain as measured with the FLACC scores and crying time. Consolability factors are felt to have some influence.

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