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. 2010 Jan;1(1):47-51.
doi: 10.1007/s13193-010-0011-0. Epub 2010 Aug 7.

Long-term outcomes after ROLL lumpectomy

H S J Ramesh, S Anguille, S Poonawala, O Harris, S Desmond, R Thind, L S Chagla, R A Audisio

Long-term outcomes after ROLL lumpectomy

H S J Ramesh et al. Indian J Surg Oncol. 2010 Jan.

Abstract

Background: Occult breast lesions are being successfully targeted by means of Radioactive-guided Occult Lesion Localization (ROLL). Several reports demonstrate suitability of ROLL technique to excise non-palpable breast lesions with immediate advantages.

Aim: Evaluation of long-term outcomes after ROLL guided lumpectomy for early breast cancer. MATERIALS AND METHODS A CONSECUTIVE SERIES OF NON PALPABLE EARLY INVASIVE BREAST CANCERS EXCISED WITH ROLL (151 PTS; DECEMBER 2002#ENTITYSTARTX02013;JUNE 2006) WERE FOLLOWED UP FOR LONG-TERM OUTCOMES, I.E. LOCAL AND/OR SYSTEMIC RECURRENCE. OUR FOLLOW-UP PROTOCOL INCLUDED 6 MONTHLY PHYSICIAN ADMINISTERED CLINICAL EXAMINATIONS AND 18 MONTHLY IMAGING, I.E. MAMMOGRAM. BONE SCAN, LIVER AND BRAIN IMAGING WERE REQUESTED ON CLINICAL NEED. CLINICAL AND/OR RADIOLOGICAL SUSPICIOUS LESIONS FOR LOCAL RECURRENCE WERE CONFIRMED PATHOLOGICALLY:

Results: The median follow-up was 46 months with all patients having a minimum 22 months follow-up. 3/151 local recurrences occurred (1.98%).

Conclusions: Long-term outcomes, i.e. local recurrence of invasive breast cancer excised with ROLL guidance compares well with existing localization techniques.

Keywords: Breast cancer; Local recurrence; Localization; Long-term outcomes; Lumpectomy; ROLL; Radioisotopes; Recurrence.

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