Pulmonary infiltrates with eosinophilia syndrome in ibuprofen overdose

Abstract

We describe the case of a 45-year-old female who developed pulmonary infiltrates and mild eosinophilia following an overdose of ibuprofen. We believe this was a case of pulmonary infiltrates with eosinophilia (PIE) syndrome and discuss the relevant literature. Although rare, PIE syndrome should be considered in those taking nonsteroidal anti-inflammatories who develop unexplained pulmonary infiltrates.