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. 2012 Aug 1;1(5):789-790.
doi: 10.4161/onci.19787.

Tumor high endothelial venules (HEVs) predict lymphocyte infiltration and favorable prognosis in breast cancer

Ludovic Martinet  1 , Ignacio Garrido, Jean-Philippe Girard
Affiliations

Tumor high endothelial venules (HEVs) predict lymphocyte infiltration and favorable prognosis in breast cancer

Ludovic Martinet et al. Oncoimmunology. .

Abstract

Lymphocyte migration into tumors remains poorly understood, despite the critical impact of these cells on cancer clinical outcome. Our recent study demonstrates the presence of blood vessels specialized in lymphocyte recruitment called high endothelial venules (HEVs) in human solid tumors and their correlation with lymphocyte infiltration and favorable prognosis in breast cancer.

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Figures

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Figure 1. Role of tumor HEVs in breast cancer.
See this image and copyright information in PMC

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