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. 2012 Sep;11(9):655-6.
doi: 10.1038/nrd3822.

Down's syndrome and Alzheimer's disease: towards secondary prevention

Seth Ness  1 , Michael Rafii, Paul Aisen, Michael Krams, Wayne Silverman, Husseini Manji
Affiliations

Down's syndrome and Alzheimer's disease: towards secondary prevention

Seth Ness et al. Nat Rev Drug Discov. 2012 Sep.

Abstract

A public-private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions.

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References

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    1. Sci Transl Med. 2012 Mar 7;4(124):124ra29 - PubMed
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