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. 2012 Aug 31;150(5):875-7.
doi: 10.1016/j.cell.2012.08.006.

Holding on through DNA replication: histone modification or modifier?

Susan M Abmayr, Jerry L Workman
Free article
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Holding on through DNA replication: histone modification or modifier?

Susan M Abmayr et al. Cell. .
Free article

Abstract

Histone methylation is widely believed to contribute to epigenetic inheritance by persevering through DNA replication and subsequently templating methylation of daughter chromosome regions. However, a report in this issue (Petruk et al.) suggests that chromatin association of the methytransferase complexes themselves persists through replication and re-establishes histone methylation.

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