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. 2013 Feb;68(2):192-4.
doi: 10.1136/thoraxjnl-2012-202071. Epub 2012 Sep 1.

Long-acting β-agonist prescribing in people with asthma in primary care

Daniel R Morales  1 , Cathy Jackson, Shona Fielding, Bruce Guthrie
Affiliations

Long-acting β-agonist prescribing in people with asthma in primary care

Daniel R Morales et al. Thorax. 2013 Feb.

Abstract

Long-acting β2-agonist (LABA) monotherapy is contraindicated in asthma following reports of serious adverse events. Anonymised Scottish health data were used to determine the prevalence of LABA prescribing and LABA monotherapy (sustained and episodic) in asthma during 2006. Of 73 486 asthma patients identified, 5592 (7.6%; 95% CI 7.4% to 7.8%) were prescribed LABAs as a separate inhaler of which 991 patients had LABA monotherapy (17.7% (95% CI 16.7% to 18.7%) of patients at risk). Asthma reviews were associated with reductions in sustained (OR 0.44; 95% CI 0.32 to 0.61) but not episodic monotherapy (OR 1.16; 95% CI 0.85 to 1.57). These findings support recent changes in UK asthma guidelines recommending LABAs in fixed-dose combination inhalers.

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