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Comment
. 2012 Sep;14(9):904-6.
doi: 10.1038/ncb2569.

Regulating intraflagellar transport

Lotte B Pedersen  1 , Søren T Christensen
Affiliations
Comment

Regulating intraflagellar transport

Lotte B Pedersen et al. Nat Cell Biol. 2012 Sep.

Abstract

Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.

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