A red baby should not be taken too lightly

Abstract

Aim: To identify clinical and laboratory features that can drive the differential diagnosis of a primary immunodeficiency diseases in patients with ectodermal defects.

Methods: Analysis of selected teaching cases.

Results: We identified four exemplary cases that allowed to point out specific clues.

Conclusions: A careful evaluation of immune and ectodermal signs is the key to the diagnosis. Therefore, a multidisciplinary approach can lead to diagnosis and to an appropriate treatment in most of the cases.