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. 2013 Mar;9(1):5-6.
doi: 10.1007/s11302-012-9330-7. Epub 2012 Sep 5.

The ATP or the natural history of neurotransmission

Ricardo Borges  1
Affiliations

The ATP or the natural history of neurotransmission

Ricardo Borges. Purinergic Signal. 2013 Mar.
No abstract available

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Figures

Fig. 1
Fig. 1
ATP behaves as a non-ideal solute for creating osmotic forces. Plots show the osmolarit0y exhibited by Na–ATP and a mixture of ATP: norepinephrine at a proportion 1/2.8. These experiments were conducted by Dr. Edward Westhead using a vapour-phase osmometer during the short visit that he just run to my laboratory
See this image and copyright information in PMC

References

    1. Borges R. The rat adrenal gland in the study of the control of catecholamine secretion. Semin Cell Dev Biol. 1997;8:113–120. doi: 10.1006/scdb.1996.0130. - DOI - PubMed
    1. Borges R, Travis ER, Hochstetler SE, Wightman RM. Effects of external osmotic pressure on vesicular secretion from bovine adrenal medullary cells. J Biol Chem. 1997;272:8325–8331. doi: 10.1074/jbc.272.45.28786. - DOI - PubMed
    1. Burnstock G. Historical review: ATP as a neurotransmitter. Trends Pharmacol Sci. 2006;27:166–176. doi: 10.1016/j.tips.2006.01.005. - DOI - PubMed
    1. Burnstock G, Verkhratsky A. Evolutionary origins of the purinergic signalling system. Acta Physiol (Oxf) 2009;195:415–447. doi: 10.1111/j.1748-1716.2009.01957.x. - DOI - PubMed
    1. Diaz-Vera J, Camacho M, Machado J, Dominguez N, Montesinos M, Hernandez-Fernaud J, Lujan R, Borges R. Chromogranins A and B are key proteins in amine accumulation but the catecholamine secretory pathway is conserved without them. FASEB J. 2012;26(1):430–438. doi: 10.1096/fj.11-181941. - DOI - PubMed

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