Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2012 Oct;87(4):741-2.
doi: 10.4269/ajtmh.2012.11-0692. Epub 2012 Sep 4.

Severe thrombotic events associated with dengue fever, Brazil

Affiliations
Case Reports

Severe thrombotic events associated with dengue fever, Brazil

Paulo Sérgio Gonçalves da Costa et al. Am J Trop Med Hyg. 2012 Oct.

Abstract

Dengue fever has been a major problem in hospital settings in Brazil for the past 15 years. The main concern has been the severe forms, i.e., dengue hemorrhagic fever and dengue shock syndrome. Hemorrhagic events of different degrees have also been a major concern. We report five cases of large vein thrombotic events associated with the acute phase of dengue fever, including a previously non-reported case of mesenteric vein thrombosis. Complications such as these could have been overlooked in the diagnosis of dengue fever, given that the major concern is the hemorrhagic event.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
T1-weighted cholangio-magnetic resonance image with contrast of dengue patient 5 showing the superior mesenteric vein (SMV) with a large thrombus (arrow) occupying the vein lumen. SMA = superior mesenteric artery; IVC = inferior vena cava; Ao = aorta.

References

    1. Cavalcanti LP, Coelho IC, Vilar DC, Holanda SG, Escóssia KN, Souza-Santos R. Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil. Rev Soc Bras Med Trop. 2010;43:355–358. - PubMed
    1. Vilela AP, Figueiredo LB, dos Santos JR, Eiras AE, Bonjardin CA, Ferreira PC, Kroon EG. Dengue virus 3 genotype I in Aedes aegypti mosquitoes and eggs, Brazil 2005–2006. Emerg Infect Dis. 2010;16:989–992. - PMC - PubMed
    1. Mairuhu AT, Mac Gillavry MR, Setiati TE, Soemantri A, ten Cate H, Brandjes DP, van Gorp EC. Is clinical outcome of dengue-virus infections influenced by coagulation and fibrinolysis? A critical review of the evidence. Lancet Infect Dis. 2003;3:33–41. - PubMed
    1. Wills BA, Oragui EE, Stephens AC, Daramola OA, Dung NM, Loan HT, Chau NV, Chambers M, Stepniewska K, Farrar JJ, Levin M. Coagulation abnormalities in dengue hemorrhagic fever: serial investigations in 167 Vietnamese children with dengue shock syndrome. CID. 2002;35:277–285. - PubMed
    1. Martina BE, Koraka P, Osterhaus AD. Dengue virus pathogenesis: an integrated view. Clin Microbiol Rev. 2009;22:564–581. - PMC - PubMed

Publication types