Case Reports
Treatment of clomipramine-induced anorgasmia with yohimbine: a case report
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- PMID: 2295589
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Case Reports
Treatment of clomipramine-induced anorgasmia with yohimbine: a case report
J Clin Psychiatry.
1990 Jan.
Abstract
Clomipramine (a tricyclic antidepressant with significant serotonin activity) causes a high incidence of anorgasmia. The authors describe the successful treatment of clomipramine-induced anorgasmia with yohimbine (an enhancer of norepinephrine activity) in a patient with obsessive compulsive disorder and major depression. The significance of this finding for the clinical management of antidepressant-induced sexual dysfunction and the impact of serotonergic-noradrenergic interaction on male sexual functioning are discussed.
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