Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Aug 29;1(1):29.
doi: 10.1186/2047-2994-1-29.

"Save Antibiotics, Save lives": an Indian success story of infection control through persuasive diplomacy

Affiliations

"Save Antibiotics, Save lives": an Indian success story of infection control through persuasive diplomacy

A Ghafur et al. Antimicrob Resist Infect Control. .

Abstract

Background: Carbapenem resistant Enterobacteriaceae is a worldwide threat, with increasing prevalence in many countries. Restricted usage of higher end antibiotics, especially carbapenem is of great importance in tackling these super bugs. Purpose of this retrospective study was to analyse the impact of antibiotic stewardship activities on the prevalence of carbapenem resistant Enterobacteriaceae in our hospital.

Findings: In the first Quarter of 2009, average usage of carbapenem group of antibiotics was 955 vials a month while in 2010, the usage dropped to 745 vials per month. Carbapenem resistant E.coli rate dropped from 3.7% in 2009 to 1.6% in 2010 and Klebsiella rate reduced from 6% in 2009 to 3.6% in 2010.

Conclusions: Strict antibiotic stewardship strategies in conjunction with good infection control practices are useful in restricting higher end antibiotic usage and reducing the prevalence of carbapenem resistant Enterobacteriaceae.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Higher end antibiotics daily check list digitally recorded.
Figure 2
Figure 2
Example of a daily check list of higher end antibiotics.
Figure 3
Figure 3
Higher end antibiotic usage tracking process.

Similar articles

Cited by

References

    1. Boucher HW. et al.Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America -IDSA Report on Development Pipeline. Clin Infcet Dis. 2009;48:1–12. doi: 10.1086/595011. - DOI - PubMed
    1. Kumarasamy KK, Toleman MA, Walsh TR. et al.Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis. 2010;10:597–602. doi: 10.1016/S1473-3099(10)70143-2. - DOI - PMC - PubMed
    1. Deshpande P, Rodrigues C, Shetty A, Kapadia F, Hegde A, Soman R. New Delhi Metallo-b lactamase (NDM-1) in Enterobacteriaceae: Treatment options with Carbapenems Compromised. JAPI. 2010;58:146–148. - PubMed
    1. Bratu S, Brooks S, Burney S. et al.Detection and spread of Escherichia coli possessing the plasmid-borne carbapenemase KPC-2 in Brooklyn, New York. Clin Infect Dis. 2007;44:972–975. doi: 10.1086/512370. - DOI - PubMed
    1. Pournaras S, Protonotariou E, Voulgari E. et al.Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece. J Antimicrob Chemother. 2009;64:348–352. doi: 10.1093/jac/dkp207. - DOI - PubMed

LinkOut - more resources