The clathrin adaptor complex responsible for somatodendritic protein sorting
- PMID: 22958815
- PMCID: PMC3467012
- DOI: 10.1016/j.neuron.2012.08.023
The clathrin adaptor complex responsible for somatodendritic protein sorting
Abstract
Neuronal proteins contain "address labels" that govern their localization. In this issue of Neuron, Farías et al. (2012) identify the machinery that recognizes one class of dendritic localization signals and establish its role in the polarization of dendritic proteins, including several postsynaptic receptors.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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Signal-mediated, AP-1/clathrin-dependent sorting of transmembrane receptors to the somatodendritic domain of hippocampal neurons.Neuron. 2012 Sep 6;75(5):810-23. doi: 10.1016/j.neuron.2012.07.007. Neuron. 2012. PMID: 22958822 Free PMC article.
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