Epithelial stem cells in the esophagus: who needs them?
- PMID: 22958926
- DOI: 10.1016/j.stem.2012.08.005
Epithelial stem cells in the esophagus: who needs them?
Abstract
In their recent Science publication, Doupé et al. (2012) demonstrate that a single population of proliferating progenitor cells is solely responsible for homeostatic self-renewal and repair of injured esophageal epithelium. These findings argue against an obligate requirement for long-lived (reserve) stem cells in adult epithelia.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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A single progenitor population switches behavior to maintain and repair esophageal epithelium.Science. 2012 Aug 31;337(6098):1091-3. doi: 10.1126/science.1218835. Epub 2012 Jul 19. Science. 2012. PMID: 22821983 Free PMC article.
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