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Review
. 2013 Jan 10:40:70-82.
doi: 10.1016/j.pnpbp.2012.08.011. Epub 2012 Aug 30.

Ghrelin and eating disorders

Deniz Atalayer  1 , Charlisa Gibson, Alexandra Konopacka, Allan Geliebter
Affiliations
Review

Ghrelin and eating disorders

Deniz Atalayer et al. Prog Neuropsychopharmacol Biol Psychiatry. .

Abstract

There is growing evidence supporting a multifactorial etiology that includes genetic, neurochemical, and physiological components for eating disorders above and beyond the more conventional theories based on psychological and sociocultural factors. Ghrelin is one of the key gut signals associated with appetite, and the only known circulating hormone that triggers a positive energy balance by stimulating food intake. This review summarizes recent findings and several conflicting reports on ghrelin in eating disorders. Understanding these findings and inconsistencies may help in developing new methods to prevent and treat patients with these disorders.

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