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Case Reports
. 2012 Sep 7:2012:bcr1220115285.
doi: 10.1136/bcr.12.2011.5285.

Idiopathic pulmonary thromboembolism in the course of intensive psychiatric inpatient care: case report and treatment guidelines

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Case Reports

Idiopathic pulmonary thromboembolism in the course of intensive psychiatric inpatient care: case report and treatment guidelines

Shane J McInerney et al. BMJ Case Rep. .

Abstract

Idiopathic thromboembolism can occur in psychiatric patients who have been inactive during a period of inpatient hospital treatment. These patients are usually treated with antipsychotic medication which has also been reported to increase risk for thromboembolic disease. Here the authors describe a patient with neither prior history of thromboembolism nor any medical risk factors for thromboembolic disease, who was admitted with an acute relapse of psychotic illness. During the course of her intensive psychiatric treatment, she had chest pain and CT-pulmonary arteriogram revealed bilateral lower lobe pulmonary embolism. She was anticoagulated and made a full medical recovery. Treatment with high dosages of typical and atypical antipsychotic medication and a lack of mobility related to intensive nursing care and sedation were likely risk factors in her development of pulmonary emboli.

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Conflict of interest statement

Competing interests: None.

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References

    1. Hägg S, Spigset O, Söderström TG. Association of venous thromboembolism and clozapine. Lancet 2000;355:1155–6. - PubMed
    1. Zornberg GL, Jick H. Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study. Lancet 2000;356:1219–23. - PubMed
    1. Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ 2010;341:c4245. - PubMed
    1. Thomassen R, Vandenbroucke JP, Rosendaal FR. Anti-psychotic medication and venous thrombosis. Br J Psychiatry 2001;179:63–6. - PubMed
    1. Boullin DJ, Orr MW, Peters JR. The platelet as a model for investigating the clinical efficacy of centrally acting drugs: relations between platelet aggregation and clinical condition in schizophrenics treated with chlorpromazine. In: de Gaetano G, Garattini S, eds. Platelets: A Multidisciplinary Approach. New York: Raven Press; 1978:389–410.

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