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. 2013 Aug;20(4):370-6.
doi: 10.1177/1553350612458544. Epub 2012 Sep 10.

Breast reconstruction with autologous fat graft mixed with platelet-rich plasma

Pietro Gentile  1 , Camilla Di Pasquali, Ilaria Bocchini, Micol Floris, Tati Eleonora, Valeria Fiaschetti, Roberto Floris, Valerio Cervelli
Affiliations

Breast reconstruction with autologous fat graft mixed with platelet-rich plasma

Pietro Gentile et al. Surg Innov. 2013 Aug.

Abstract

Background: The purpose of this study was to review the authors' experience of fat grafting, evaluating the effects related to the use of fat grafting with platelet-rich plasma (PRP) in the improvement of fat volume in breast reconstruction and comparing the results with a control group (only centrifuged fat grafting).

Methods: A total of 50 patients aged between 19 and 60 years affected by breast soft-tissue defects were analyzed at the Plastic and Reconstructive Department of the University of Tor Vergata. They were treated with fat grafting + PRP. The control group (50 patients with breast soft-tissue defects) were treated with centrifuged fat grafting injection according to Coleman's procedure.

Results: The patients treated with PRP added to the autologous fat grafts showed a 69% maintenance of the contour restoring and of 3-dimensional volume after 1 year, whereas the patients of the control group treated with centrifuged fat grafting showed a 39% maintenance.

Conclusion: PRP mixed with fat grafting leads to an improvement in maintaining breast volume in patients affected by breast soft-tissue defects.

Keywords: PRP; breast fat graft; fat graft with platelet-rich plasma; platelet-rich plasma.

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Comment in

  • Platelet-rich plasma in surgical oncology.
    Spartalis ED, Tomos P, Dimitroulis D, Kouraklis G. Spartalis ED, et al. Surg Innov. 2014 Aug;21(4):441. doi: 10.1177/1553350613520516. Epub 2014 Feb 3. Surg Innov. 2014. PMID: 24496102 No abstract available.